منابع مشابه
Citrate in pediatric CNS tumors?
BACKGROUND AND PURPOSE In a subset of in vivo MR spectra acquired from pediatric brain tumors, we have observed an unassigned peak. The goal of this study was to determine the molecule of origin, and the prevalence and concentration of this chemical in various pediatric brain tumors. MATERIALS AND METHODS Single-voxel point-resolved spectroscopy (PRESS) spectra from 85 patients with brain tum...
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Temozolomide (tmz) is an oral alkylating agent that received accelerated approval from the U.S. Food and Drug Administration in 1999 because of its promising activity in high-grade glioma (hgg) in adults. A European Organisation for Research and Treatment of Cancer randomized trial eventually confirmed a significant survival benefit in adults with newly diagnosed glioblastoma multiforme when tm...
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Introduction Despite significant treatment advances and survival improvement in a variety of pediatric CNS tumors, there remains a large number of children who succumb to their disease. A variety of novel biologic and targeted therapies have been evaluated in an effort to improve survival. One class of therapeutics that is being widely explored is antiangiogenic agents. Angiogenesis is the deve...
متن کاملCRUSH PREPARATION CYTOLOGIC FINDINGS OF CNS TUMORS: A STUDY OF 199 CASES
Crush preparation cytology technique was used during the operative procedure for the diagnosis of 199 CNS tumors. This technique is simple, easy to perform, rapid, and inexpensive. The cytomorphologic findings were excellent and helped achieve a rapid and correct diagnosis. This technique was used on the tiny, small specimens which were not suitable for frozen sectioning. The results were c...
متن کاملGenetics of Pediatric Bone Tumors: a Systematic Review
Background: Understanding the differences in genetics of malignancies is crucial for therapeutic decisions. This systematic review was conducted to evaluate the current evidence on genetics of bone tumors in the context of pediatric cancer. Material and Methods: We performed a systematic review of the literature published on genetics of pediatrics bone tumors, using PubMed, Google scholar,...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 2004
ISSN: 0007-0920,1532-1827
DOI: 10.1038/sj.bjc.6602135